Dr Hogarth developed an interest in research early in her career for which she was awarded a B.Sc. Honours Degree in Medical Cell Biology. She has subsequently been involved in both clinical and laboratory-based research. She has carried out several clinical studies. These have included clinical trials investigating the effect of nutritional supplementation in the elderly and febuxostat as a treatment for gout, as well as the assessment of autonomic function in patients with systemic lupus erythematosus, the use of inflammatory markers as measures of the acute phase response and new treatments for gout. This has led to publications in peer reviewed journals as listed below.
In 1993, she was awarded a prestigious Medical Research Council Fellowship which led to the award of a PhD Degree from the University of London. Her thesis was laboratory-based, and involved the identification of potential genetic markers of susceptibility to systemic lupus erythematosus, an inflammatory joint and muscle disease.
Since being appointed as a Consultant Rheumatologist, she has concentrated on education and teaching at both Undergraduate and Postgraduate levels and is the Rheumatology lead for Undergraduate Teaching at Ealing Hospital. She is involved in recruiting patients for clinical trials in osteoarthritis and inflammatory arthritis both locally and nationally, and is involved with the BSBR National Register which monitors the safety and long term side effects of new biological treatments.
Hogarth MB, Thomas S, Seifert MH and Tariq S. Reiter’s syndrome following intravesical BCG immunotherapy. Postgrad Med J (2004) 76 791-33
Hogarth MB, Qureshi T, Lloyd J and Rees RG. A blistering rash and painful knees. Lancet (1999) 353 978-9
Hogarth MB, Gallimore JR, Savage P, Palmer AJ, Starr J, Bulpitt CJ and Pepys MB. CRP and SAA as markers of the acute phase response in the elderly. Age and Ageing (1997) 26 153-8
Hogarth MB, Marshall P, Lovatt LB, Palmer AJ, Frost CG, Fletcher AE, Nicholl CG and Bulpitt CJ.. Nutritional Supplementation in elderly medical inpatients. A double blind placebo controlled trial. Age and Ageing (1996) 25 453-7
Thein M, Hogarth MB, Acland K. Seronegative arthritis associated with the follicular occlusion triad. Clin Exp Dermatol. 2004 Sep;29(5):550-2
Feher MD, Hepburn AL, Hogarth MB, Ball SG, Kaye S. Fenofibrate enhances urate reduction in men treated with allopurinol for hyperuricaemia and gout. Rheumatology (Oxford). 2003 Feb;42(2):321-5
Salaman M, Mawer DPC, Hogarth MB, Seifert MH and Isenberg D. Counter proliferative effects of nucleosomal antigens in cultures from lupus patients. Lupus (2001) 10 332-9
Macanovic M, Hogarth MB, and Lachmann PJ. Anti-DNA Antibodies in the urine of lupus nephritis patients. Nephrol Dial transplant (1999) 14 1418-24
Naysmith DG, Pickersgill A, and Hogarth MB.. Reducing the hours of work of pre-registration house officers: A report on the shift system. BMJ (1991) 30 93-4